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A crossover study evaluating the sex‐dependent and sensitizing effects of sleep deprivation using a nociceptive test battery in healthy subjects

AIM: We assessed whether total sleep deprivation (TSD) in combination with pain tests yields a reliable method to assess altered pain thresholds, which subsequently may be used to investigate (novel) analgesics in healthy subjects. METHODS: This was a two‐part randomized crossover study in 24 health...

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Detalles Bibliográficos
Autores principales: Hijma, Hemme, Koopmans, Ingrid, Klaassen, Erica, Doll, Robert Jan, Zuiker, Rob, Groeneveld, Geert Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086808/
https://www.ncbi.nlm.nih.gov/pubmed/35997713
http://dx.doi.org/10.1111/bcp.15505