Valproic acid determination by liquid chromatography coupled to mass spectrometry (LC–MS/MS) in whole blood for forensic purposes

Valproic acid (VPA) is a well‐known drug prescribed as anti‐epileptic. It has a narrow therapeutic range and shows great individual differences in pharmacodynamics and pharmacokinetics. Consequently, the therapeutical drug monitoring (TDM) in patient's plasma is of crucial importance. Liquid ch...

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Detalles Bibliográficos
Autores principales: Pascali, Jennifer P., Giorgetti, Arianna, Barone, Rossella, Pelletti, Guido, Fais, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086813/
https://www.ncbi.nlm.nih.gov/pubmed/36028251
http://dx.doi.org/10.1002/dta.3362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086813/
https://www.ncbi.nlm.nih.gov/pubmed/36028251
http://dx.doi.org/10.1002/dta.3362

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