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Valproic acid determination by liquid chromatography coupled to mass spectrometry (LC–MS/MS) in whole blood for forensic purposes
Valproic acid (VPA) is a well‐known drug prescribed as anti‐epileptic. It has a narrow therapeutic range and shows great individual differences in pharmacodynamics and pharmacokinetics. Consequently, the therapeutical drug monitoring (TDM) in patient's plasma is of crucial importance. Liquid ch...
Autores principales: | Pascali, Jennifer P., Giorgetti, Arianna, Barone, Rossella, Pelletti, Guido, Fais, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086813/ https://www.ncbi.nlm.nih.gov/pubmed/36028251 http://dx.doi.org/10.1002/dta.3362 |
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