Single‐molecule tracking of perfringolysin O assembly and membrane insertion uncoupling

We exploit single‐molecule tracking and optical single channel recording in droplet interface bilayers to resolve the assembly pathway and pore formation of the archetypical cholesterol‐dependent cytolysin nanopore, Perfringolysin O. We follow the stoichiometry and diffusion of Perfringolysin O comp...

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Detalles Bibliográficos
Autores principales: Senior, Michael J. T., Monico, Carina, Weatherill, Eve E., Gilbert, Robert J., Heuck, Alejandro P., Wallace, Mark I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086847/
https://www.ncbi.nlm.nih.gov/pubmed/35989549
http://dx.doi.org/10.1111/febs.16596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086847/
https://www.ncbi.nlm.nih.gov/pubmed/35989549
http://dx.doi.org/10.1111/febs.16596

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