Cargando…
Single‐molecule tracking of perfringolysin O assembly and membrane insertion uncoupling
We exploit single‐molecule tracking and optical single channel recording in droplet interface bilayers to resolve the assembly pathway and pore formation of the archetypical cholesterol‐dependent cytolysin nanopore, Perfringolysin O. We follow the stoichiometry and diffusion of Perfringolysin O comp...
Autores principales: | Senior, Michael J. T., Monico, Carina, Weatherill, Eve E., Gilbert, Robert J., Heuck, Alejandro P., Wallace, Mark I. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086847/ https://www.ncbi.nlm.nih.gov/pubmed/35989549 http://dx.doi.org/10.1111/febs.16596 |
Ejemplares similares
-
Mechanistic Insights into the Cholesterol-dependent Binding of Perfringolysin O-based Probes and Cell Membranes
por: Johnson, Benjamin B., et al.
Publicado: (2017) -
Interaction of Cholesterol with Perfringolysin O: What Have We Learned from Functional Analysis?
por: Savinov, Sergey N., et al.
Publicado: (2017) -
Single-molecule analysis of the entire perfringolysin O pore formation pathway
por: McGuinness, Conall, et al.
Publicado: (2022) -
Perfringolysin O: The Underrated Clostridium perfringens Toxin?
por: Verherstraeten, Stefanie, et al.
Publicado: (2015) -
Domain 4 (D4) of Perfringolysin O to Visualize Cholesterol in Cellular Membranes—The Update
por: Maekawa, Masashi
Publicado: (2017)