Switching positions: Assessing the dynamics of conjugational heterogeneity in antibody–drug conjugates using CE‐SDS

Antibody–drug conjugates (ADCs) are a prospective class of new oncology therapeutics with the ability to deliver a cytotoxic drug to a targeted location. The concept appears simple, but ADCs are highly complex due to their intrinsic heterogeneity. Randomly conjugated ADCs, for instance, are composed...

Descripción completa

Detalles Bibliográficos
Autores principales: van den Berg, Eline B. A., Hendriks, Jaap C. W., Elsinga, Everdine W., Eggink, Mark, Dirksen, Eef H. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
General, Ce & Cec
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086850/
https://www.ncbi.nlm.nih.gov/pubmed/35907250
http://dx.doi.org/10.1002/elps.202200140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086850/
https://www.ncbi.nlm.nih.gov/pubmed/35907250
http://dx.doi.org/10.1002/elps.202200140

Ejemplares similares