Evaluation of Deutetrabenazine's Potential to Delay Cardiac Repolarization Using Concentration‐QTc Analysis

Deutetrabenazine (Austedo) is indicated in adults for chorea associated with Huntington disease and tardive dyskinesia. Escalating deutetrabenazine doses were administered to healthy volunteers who were cytochrome P450 2D6 extensive/intermediate metabolizers (EMs) or poor metabolizers (PMs) to deter...

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Detalles Bibliográficos
Autores principales: Schneider, Frank, Darpo, Borje, Loupe, Pippa S., Xue, Hongqi, Knebel, Helena, Gutierrez, Maria, Gordon, Mark Forrest, Rabinovich‐Guilatt, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086964/
https://www.ncbi.nlm.nih.gov/pubmed/36098670
http://dx.doi.org/10.1002/cpdd.1161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086964/
https://www.ncbi.nlm.nih.gov/pubmed/36098670
http://dx.doi.org/10.1002/cpdd.1161

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