IL1RAP expression and the enrichment of IL‐33 activation signatures in severe neutrophilic asthma

BACKGROUND: Interleukin (IL)‐33 is an upstream regulator of type 2 (T2) eosinophilic inflammation and has been proposed as a key driver of some asthma phenotypes. OBJECTIVE: To derive gene signatures from in vitro studies of IL‐33‐stimulated cells and use these to determine IL‐33‐associated enrichme...

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Detalles Bibliográficos
Autores principales: Badi, Yusef Eamon, Salcman, Barbora, Taylor, Adam, Rana, Batika, Kermani, Nazanin Zounemat, Riley, John H., Worsley, Sally, Mumby, Sharon, Dahlen, Sven‐Eric, Cousins, David, Bulfone‐Paus, Silvia, Affleck, Karen, Chung, Kian Fan, Bates, Stewart, Adcock, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086999/
https://www.ncbi.nlm.nih.gov/pubmed/35986608
http://dx.doi.org/10.1111/all.15487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086999/
https://www.ncbi.nlm.nih.gov/pubmed/35986608
http://dx.doi.org/10.1111/all.15487

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