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IL1RAP expression and the enrichment of IL‐33 activation signatures in severe neutrophilic asthma
BACKGROUND: Interleukin (IL)‐33 is an upstream regulator of type 2 (T2) eosinophilic inflammation and has been proposed as a key driver of some asthma phenotypes. OBJECTIVE: To derive gene signatures from in vitro studies of IL‐33‐stimulated cells and use these to determine IL‐33‐associated enrichme...
Autores principales: | Badi, Yusef Eamon, Salcman, Barbora, Taylor, Adam, Rana, Batika, Kermani, Nazanin Zounemat, Riley, John H., Worsley, Sally, Mumby, Sharon, Dahlen, Sven‐Eric, Cousins, David, Bulfone‐Paus, Silvia, Affleck, Karen, Chung, Kian Fan, Bates, Stewart, Adcock, Ian M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086999/ https://www.ncbi.nlm.nih.gov/pubmed/35986608 http://dx.doi.org/10.1111/all.15487 |
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