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Prediction of Longitudinal Cognitive Decline in Preclinical Alzheimer Disease Using Plasma Biomarkers

IMPORTANCE: Alzheimer disease (AD) pathology starts with a prolonged phase of β-amyloid (Aβ) accumulation without symptoms. The duration of this phase differs greatly among individuals. While this disease phase has high relevance for clinical trial designs, it is currently unclear how to best predic...

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Detalles Bibliográficos
Autores principales: Mattsson-Carlgren, Niklas, Salvadó, Gemma, Ashton, Nicholas J., Tideman, Pontus, Stomrud, Erik, Zetterberg, Henrik, Ossenkoppele, Rik, Betthauser, Tobey J., Cody, Karly Alex, Jonaitis, Erin M., Langhough, Rebecca, Palmqvist, Sebastian, Blennow, Kaj, Janelidze, Shorena, Johnson, Sterling C., Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087054/
https://www.ncbi.nlm.nih.gov/pubmed/36745413
http://dx.doi.org/10.1001/jamaneurol.2022.5272