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Prediction of Longitudinal Cognitive Decline in Preclinical Alzheimer Disease Using Plasma Biomarkers
IMPORTANCE: Alzheimer disease (AD) pathology starts with a prolonged phase of β-amyloid (Aβ) accumulation without symptoms. The duration of this phase differs greatly among individuals. While this disease phase has high relevance for clinical trial designs, it is currently unclear how to best predic...
Autores principales: | Mattsson-Carlgren, Niklas, Salvadó, Gemma, Ashton, Nicholas J., Tideman, Pontus, Stomrud, Erik, Zetterberg, Henrik, Ossenkoppele, Rik, Betthauser, Tobey J., Cody, Karly Alex, Jonaitis, Erin M., Langhough, Rebecca, Palmqvist, Sebastian, Blennow, Kaj, Janelidze, Shorena, Johnson, Sterling C., Hansson, Oskar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Medical Association
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087054/ https://www.ncbi.nlm.nih.gov/pubmed/36745413 http://dx.doi.org/10.1001/jamaneurol.2022.5272 |
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