A comprehensive pharmacogenomic study indicates roles for SLCO1B1, ABCG2 and SLCO2B1 in rosuvastatin pharmacokinetics

AIMS: The aim was to comprehensively investigate the effects of genetic variability on the pharmacokinetics of rosuvastatin. METHODS: We conducted a genome‐wide association study and candidate gene analyses of single dose rosuvastatin pharmacokinetics in a prospective study (n = 159) and a cohort of...

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Detalles Bibliográficos
Autores principales: Lehtisalo, Minna, Taskinen, Suvi, Tarkiainen, E. Katriina, Neuvonen, Mikko, Viinamäki, Jenni, Paile‐Hyvärinen, Maria, Lilius, Tuomas O., Tapaninen, Tuija, Backman, Janne T., Tornio, Aleksi, Niemi, Mikko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087178/
https://www.ncbi.nlm.nih.gov/pubmed/35942816
http://dx.doi.org/10.1111/bcp.15485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087178/
https://www.ncbi.nlm.nih.gov/pubmed/35942816
http://dx.doi.org/10.1111/bcp.15485

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