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A pharmacometrics model to define docetaxel target in early breast cancer

AIMS: We aimed to study the relation between pharmacokinetics (PK) and pharmacodynamics (PD) of docetaxel in early breast cancer and recommend a target exposure. METHODS: A PK/PD study was performed in 27 early breast cancer patients treated with doxorubicin and cyclophosphamide for 4 cycles followe...

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Detalles Bibliográficos
Autores principales: Aldaz, Azucena, Schaiquevich, Paula, Aramendía, José Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087179/
https://www.ncbi.nlm.nih.gov/pubmed/36098504
http://dx.doi.org/10.1111/bcp.15526