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Defining the pig microglial transcriptome reveals its core signature, regional heterogeneity, and similarity with human and rodent microglia

Microglia play key roles in brain homeostasis as well as responses to neurodegeneration and neuroinflammatory processes caused by physical disease and psychosocial stress. The pig is a physiologically relevant model species for studying human neurological disorders, many of which are associated with...

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Detalles Bibliográficos
Autores principales: Shih, Barbara B., Brown, Sarah M., Barrington, Jack, Lefevre, Lucas, Mabbott, Neil A., Priller, Josef, Thompson, Gerard, Lawrence, Alistair B., McColl, Barry W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087207/
https://www.ncbi.nlm.nih.gov/pubmed/36120803
http://dx.doi.org/10.1002/glia.24274