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Structural studies offer a framework for understanding the role of properdin in the alternative pathway and beyond
Structures of alternative pathway proteins have offered a comprehensive structural basis for understanding the molecular mechanisms governing activation and regulation of the amplification pathway of the complement cascade. Although properdin (FP) is required in vivo to sustain a functional alternat...
Autores principales: | Pedersen, Dennis Vestergaard, Lorentzen, Josefine, Andersen, Gregers Rom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087229/ https://www.ncbi.nlm.nih.gov/pubmed/36097870 http://dx.doi.org/10.1111/imr.13129 |
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