Crystal structures of free and ligand‐bound forms of the TetR/AcrR‐like regulator SCO3201 from Streptomyces coelicolor suggest a novel allosteric mechanism

TetR/AcrR‐like transcription regulators enable bacteria to sense a wide variety of chemical compounds and to dynamically adapt the expression levels of specific genes in response to changing growth conditions. Here, we describe the structural characterisation of SCO3201, an atypical TetR/AcrR family...

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Detalles Bibliográficos
Autores principales: Werten, Sebastiaan, Waack, Paul, Palm, Gottfried J., Virolle, Marie‐Joëlle, Hinrichs, Winfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087246/
https://www.ncbi.nlm.nih.gov/pubmed/36017630
http://dx.doi.org/10.1111/febs.16606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087246/
https://www.ncbi.nlm.nih.gov/pubmed/36017630
http://dx.doi.org/10.1111/febs.16606

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