Truncated CSF3 receptors induce pro‐inflammatory responses in severe congenital neutropenia

Severe congenital neutropenia (SCN) patients are prone to develop myelodysplastic syndrome (MDS) or acute myeloid leukaemia (AML). Leukaemic progression of SCN is associated with the early acquisition of CSF3R mutations in haematopoietic progenitor cells (HPCs), which truncate the colony‐stimulating...

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Detalles Bibliográficos
Autores principales: Olofsen, Patricia A., Bosch, Dennis A., de Looper, Hans W. J., van Strien, Paulina M. H., Hoogenboezem, Remco M., Roovers, Onno, van der Velden, Vincent H. J., Bindels, Eric M. J., De Pater, Emma M., Touw, Ivo P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Paediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087386/
https://www.ncbi.nlm.nih.gov/pubmed/36168923
http://dx.doi.org/10.1111/bjh.18477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087386/
https://www.ncbi.nlm.nih.gov/pubmed/36168923
http://dx.doi.org/10.1111/bjh.18477

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