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A scoping review of evaluations of and recommendations for default uncertainty factors in human health risk assessment

Uncertainty factors (UFs) are used to account for uncertainties and variability when setting exposure limits or guidance values. Starting from a proposal of a single UF of 100 to extrapolate from an animal NOAEL to a human acceptable exposure, the aspects of uncertainty and number of UFs have divers...

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Detalles Bibliográficos
Autores principales: Johanson, Gunnar, Moto, Tshepo Paulsen, Schenk, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087398/
https://www.ncbi.nlm.nih.gov/pubmed/36017531
http://dx.doi.org/10.1002/jat.4386