Cargando…
A scoping review of evaluations of and recommendations for default uncertainty factors in human health risk assessment
Uncertainty factors (UFs) are used to account for uncertainties and variability when setting exposure limits or guidance values. Starting from a proposal of a single UF of 100 to extrapolate from an animal NOAEL to a human acceptable exposure, the aspects of uncertainty and number of UFs have divers...
Autores principales: | Johanson, Gunnar, Moto, Tshepo Paulsen, Schenk, Linda |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087398/ https://www.ncbi.nlm.nih.gov/pubmed/36017531 http://dx.doi.org/10.1002/jat.4386 |
Ejemplares similares
-
Physiologically based pharmacokinetic modeling of nanoceria systemic distribution in rats suggests dose- and route-dependent biokinetics
por: Carlander, Ulrika, et al.
Publicado: (2018) -
Model Uncertainty via the Integration of Hormesis and LNT as the Default in Cancer Risk Assessment
por: Calabrese, Edward J.
Publicado: (2015) -
Dispelling urban myths about default uncertainty factors in chemical risk assessment – sufficient protection against mixture effects?
por: Martin, Olwenn V, et al.
Publicado: (2013) -
A scoping review of practice recommendations for clinicians’ communication of uncertainty
por: Medendorp, Niki M., et al.
Publicado: (2021) -
Breastfeed or be vaccinated—an unreasonable default recommendation
por: Merewood, Anne, et al.
Publicado: (2021)