Structure‐based design, synthesis and biological evaluation of a NAD (+) analogue targeting Pseudomonas aeruginosa NAD kinase

Multidrug resistance is a major public health problem that requires the urgent development of new antibiotics and therefore the identification of novel bacterial targets. The activity of nicotinamide adenine dinucleotide kinase, NADK, is essential in all bacteria tested so far, including many human...

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Detalles Bibliográficos
Autores principales: Rahimova, Rahila, Nogaret, Pauline, Huteau, Valérie, Gelin, Muriel, Clément, David A., Labesse, Gilles, Pochet, Sylvie, Blanc‐Potard, Anne‐Béatrice, Lionne, Corinne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087438/
https://www.ncbi.nlm.nih.gov/pubmed/36036789
http://dx.doi.org/10.1111/febs.16604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087438/
https://www.ncbi.nlm.nih.gov/pubmed/36036789
http://dx.doi.org/10.1111/febs.16604

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