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Structure‐based design, synthesis and biological evaluation of a NAD (+) analogue targeting Pseudomonas aeruginosa NAD kinase
Multidrug resistance is a major public health problem that requires the urgent development of new antibiotics and therefore the identification of novel bacterial targets. The activity of nicotinamide adenine dinucleotide kinase, NADK, is essential in all bacteria tested so far, including many human...
Autores principales: | Rahimova, Rahila, Nogaret, Pauline, Huteau, Valérie, Gelin, Muriel, Clément, David A., Labesse, Gilles, Pochet, Sylvie, Blanc‐Potard, Anne‐Béatrice, Lionne, Corinne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087438/ https://www.ncbi.nlm.nih.gov/pubmed/36036789 http://dx.doi.org/10.1111/febs.16604 |
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