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Dose optimization of cefotaxime as pre‐emptive treatment in critically ill adult patients: A population pharmacokinetic study

AIMS: To describe the pharmacokinetics (PK) of cefotaxime as pre‐emptive treatment in critically ill adult patients, including covariates and to determine the probability of target attainment (PTA) of different dosage regimens for Enterobacterales and Staphylococcus aureus . METHODS: Five samples we...

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Detalles Bibliográficos
Autores principales: Roelofsen, Eveline E., Abdulla, Alan, Muller, Anouk E., Endeman, Henrik, Gommers, Diederik, Dijkstra, Annemieke, Hunfeld, Nicole G. M., de Winter, Brenda C. M., Koch, Birgit C. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087439/
https://www.ncbi.nlm.nih.gov/pubmed/35942921
http://dx.doi.org/10.1111/bcp.15487