C2‐linked alkynyl poly‐ethylene glycol(PEG) adenosine conjugates as water‐soluble adenosine receptor agonists

A series of 12 novel polyethylene‐glycol(PEG)‐alkynyl C2‐adenosine(ADN) conjugates were synthesized using a robust Sonogashira coupling protocol and characterized by NMR spectroscopy and mass spectrometry analysis. The ADN‐PEG conjugates showed null to moderate toxicity in murine macrophages and 12c...

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Detalles Bibliográficos
Autores principales: Ferguson, Lindsay, Madieh, Nasrin Shokrzadeh, Vaideanu, Alexandra, Schatzlein, Andreas, Festa, Joseph, Singh, Harprit, Wells, Geoffrey, Bhakta, Sanjib, Brucoli, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087458/
https://www.ncbi.nlm.nih.gov/pubmed/35993496
http://dx.doi.org/10.1111/cbdd.14128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087458/
https://www.ncbi.nlm.nih.gov/pubmed/35993496
http://dx.doi.org/10.1111/cbdd.14128

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