Somatic mutations reveal complex metastatic seeding from multifocal primary prostate cancer

Primary prostate cancer shows a striking intraorgan molecular heterogeneity, with multiple spatially separated malignant foci in the majority of patients. Metastatic prostate cancer, however, typically reveals more homogenous molecular profiles, suggesting a monoclonal origin of the metastatic lesio...

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Detalles Bibliográficos
Autores principales: Carm, Kristina T., Johannessen, Bjarne, Bogaard, Mari, Bakken, Anne Cathrine, Maltau, Aase V., Hoff, Andreas M., Axcrona, Ulrika, Axcrona, Karol, Lothe, Ragnhild A., Skotheim, Rolf I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
CANCER GENETICS AND EPIGENETICS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087486/
https://www.ncbi.nlm.nih.gov/pubmed/35880692
http://dx.doi.org/10.1002/ijc.34226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087486/
https://www.ncbi.nlm.nih.gov/pubmed/35880692
http://dx.doi.org/10.1002/ijc.34226

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