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Somatic mutations reveal complex metastatic seeding from multifocal primary prostate cancer
Primary prostate cancer shows a striking intraorgan molecular heterogeneity, with multiple spatially separated malignant foci in the majority of patients. Metastatic prostate cancer, however, typically reveals more homogenous molecular profiles, suggesting a monoclonal origin of the metastatic lesio...
Autores principales: | Carm, Kristina T., Johannessen, Bjarne, Bogaard, Mari, Bakken, Anne Cathrine, Maltau, Aase V., Hoff, Andreas M., Axcrona, Ulrika, Axcrona, Karol, Lothe, Ragnhild A., Skotheim, Rolf I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087486/ https://www.ncbi.nlm.nih.gov/pubmed/35880692 http://dx.doi.org/10.1002/ijc.34226 |
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