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IGFBP5 antisense and short hairpin RNA (shRNA) constructs improve erectile function by inducing cavernosum angiogenesis in diabetic mice

BACKGROUND: The incidence of diabetic erectile dysfunction (ED) is rapidly increasing, and due to the severe angiopathy caused by diabetes, current drugs are ineffective at treating ED. Insulin‐like growth factor‐binding protein 5 (IGFBP5) promotes cell death and induces apoptosis in various cell ty...

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Detalles Bibliográficos
Autores principales: Ock, Jiyeon, Suh, Jun‐Kyu, Hong, Soon‐Sun, Kang, Ju‐Hee, Yin, Guo Nan, Ryu, Ji‐Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087557/
https://www.ncbi.nlm.nih.gov/pubmed/35866351
http://dx.doi.org/10.1111/andr.13234