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Drug‐Drug Interactions With the Hepatitis B Virus Capsid Assembly Modulator JNJ‐56136379 (Bersacapavir)

The capsid assembly modulator JNJ‐56136379 (bersacapavir) disrupts hepatitis B virus replication. It is metabolized via cytochrome P450 (CYP) 3A, but little is known about the drug‐drug interactions of JNJ‐56136379 when combined with drugs that inhibit or are metabolized by CYP3A. In a phase 1, open...

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Detalles Bibliográficos
Autores principales: Vandenbossche, Joris, Yogaratnam, Jeysen, Hillewaert, Vera, Rasschaert, Freya, Talloen, Willem, Biewenga, Jeike, Snoeys, Jan, Kakuda, Thomas N., Palmer, Martyn, Nangosyah, Julius, Biermer, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087559/
https://www.ncbi.nlm.nih.gov/pubmed/36062869
http://dx.doi.org/10.1002/cpdd.1164