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Drug‐Drug Interactions With the Hepatitis B Virus Capsid Assembly Modulator JNJ‐56136379 (Bersacapavir)
The capsid assembly modulator JNJ‐56136379 (bersacapavir) disrupts hepatitis B virus replication. It is metabolized via cytochrome P450 (CYP) 3A, but little is known about the drug‐drug interactions of JNJ‐56136379 when combined with drugs that inhibit or are metabolized by CYP3A. In a phase 1, open...
Autores principales: | Vandenbossche, Joris, Yogaratnam, Jeysen, Hillewaert, Vera, Rasschaert, Freya, Talloen, Willem, Biewenga, Jeike, Snoeys, Jan, Kakuda, Thomas N., Palmer, Martyn, Nangosyah, Julius, Biermer, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087559/ https://www.ncbi.nlm.nih.gov/pubmed/36062869 http://dx.doi.org/10.1002/cpdd.1164 |
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