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Pharmacokinetics, Bioavailability, and Swallowing Safety With Riluzole Oral Film

Dysphagia is highly prevalent in patients with amyotrophic lateral sclerosis (ALS). Riluzole is a US Food and Drug Administration‐approved treatment for ALS. Riluzole oral film (ROF; Exservan™) contains riluzole in a polymer‐based film matrix. The ROF is administered by placing on the tongue, where...

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Detalles Bibliográficos
Autores principales: Wymer, James, Apple, Stephen, Harrison, Antoinette, Hill, Bryan Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087659/
https://www.ncbi.nlm.nih.gov/pubmed/36168148
http://dx.doi.org/10.1002/cpdd.1168