Cargando…

Structures of lactaldehyde reductase, FucO, link enzyme activity to hydrogen bond networks and conformational dynamics

A group‐III iron containing 1,2‐propanediol oxidoreductase, FucO, (also known as lactaldehyde reductase) from Escherichia coli was examined regarding its structure–dynamics–function relationships in the catalysis of the NADH‐dependent reduction of (2S)‐lactaldehyde. Crystal structures of FucO varian...

Descripción completa

Detalles Bibliográficos
Autores principales: Zavarise, Alberto, Sridhar, Shruthi, Kiema, Tiila‐Riikka, Wierenga, Rikkert K., Widersten, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087678/
https://www.ncbi.nlm.nih.gov/pubmed/36002154
http://dx.doi.org/10.1111/febs.16603