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Structures of lactaldehyde reductase, FucO, link enzyme activity to hydrogen bond networks and conformational dynamics
A group‐III iron containing 1,2‐propanediol oxidoreductase, FucO, (also known as lactaldehyde reductase) from Escherichia coli was examined regarding its structure–dynamics–function relationships in the catalysis of the NADH‐dependent reduction of (2S)‐lactaldehyde. Crystal structures of FucO varian...
Autores principales: | Zavarise, Alberto, Sridhar, Shruthi, Kiema, Tiila‐Riikka, Wierenga, Rikkert K., Widersten, Mikael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087678/ https://www.ncbi.nlm.nih.gov/pubmed/36002154 http://dx.doi.org/10.1111/febs.16603 |
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