KEAP1‐NRF2 protein–protein interaction inhibitors: Design, pharmacological properties and therapeutic potential

The transcription factor nuclear factor erythroid 2‐related factor 2 (NRF2) is considered the master regulator of the phase II antioxidant response. It controls a plethora of cytoprotective genes related to oxidative stress, inflammation, and protein homeostasis, among other processes. Activation of...

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Detalles Bibliográficos
Autores principales: Crisman, Enrique, Duarte, Pablo, Dauden, Esteban, Cuadrado, Antonio, Rodríguez‐Franco, María Isabel, López, Manuela G., León, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087726/
https://www.ncbi.nlm.nih.gov/pubmed/36086898
http://dx.doi.org/10.1002/med.21925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087726/
https://www.ncbi.nlm.nih.gov/pubmed/36086898
http://dx.doi.org/10.1002/med.21925

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