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Adverse maternal environment alters Oprl1 variant expression in mouse hippocampus

An adverse maternal environment (AME) and Western diet (WD) in early life predispose offspring toward cognitive impairment in humans and mice. Cognitive impairment associates with hippocampal dysfunction. An important regulator of hippocampal function is the hippocampal Nociceptin/Orphanin FQ (N/OFQ...

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Detalles Bibliográficos
Autores principales: Ke, Xingrao, Huang, Yingliu, Fu, Qi, Majnik, Amber, Sampath, Venkatesh, Lane, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087895/
https://www.ncbi.nlm.nih.gov/pubmed/35983908
http://dx.doi.org/10.1002/ar.25056