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APOBEC mutational signature predicts prognosis and immunotherapy response in nonsmoking patients with lung adenocarcinoma

BACKGROUND: Lung adenocarcinoma (LUAD) is the most common type of non-small cell lung cancer (NSCLC) with poor survival in advanced stage. Nowadays the rate of nonsmoking patients has dramatically increased and may be associated with the presence of driver mutations. Better understanding of the muta...

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Detalles Bibliográficos
Autores principales: Ma, Jianli, Yang, Xudong, Zhang, Jing, Antonoff, Mara B., Wu, Qianjiang, Ji, Hongfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088004/
https://www.ncbi.nlm.nih.gov/pubmed/37057114
http://dx.doi.org/10.21037/tlcr-23-150