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Transformation of ALK-positive NSCLC to SCLC after alectinib resistance and response to combined atezolizumab: a case report

BACKGROUND: The genotypic and histological evolution of non-small cell lung cancer (NSCLC) to small cell lung cancer (SCLC) has been described as a mechanism of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors (TKIs). However, it was extremely rare in anaplastic lym...

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Detalles Bibliográficos
Autores principales: Xia, Guohao, Huang, Jiayuan, Ni, Jie, Song, Meng, Zhang, Junling, Hofman, Paul, Christopoulos, Petros, Grenda, Anna, Huang, Mengli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088007/
https://www.ncbi.nlm.nih.gov/pubmed/37057117
http://dx.doi.org/10.21037/tlcr-23-154