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Stereoretentive Formation of Cyclobutanes from Pyrrolidines: Lessons Learned from DFT Studies of the Reaction Mechanism

[Image: see text] The stereoselective synthesis of cyclobutanes that possess an array of stereocenters in a contiguous fashion has attracted the wide interest of the synthetic community. Cyclobutanes can be generated from the contraction of pyrrolidines through the formation of 1,4-biradical interme...

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Detalles Bibliográficos
Autores principales: Monreal-Corona, Roger, Solà, Miquel, Pla-Quintana, Anna, Poater, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088030/
https://www.ncbi.nlm.nih.gov/pubmed/36940389
http://dx.doi.org/10.1021/acs.joc.3c00080