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Stereospecific Nickel-Catalyzed Cross-Electrophile Coupling Reaction of Alkyl Mesylates and Allylic Difluorides to Access Enantioenriched Vinyl Fluoride-Substituted Cyclopropanes

[Image: see text] Cross-electrophile coupling reactions involving direct C–O bond activation of unactivated alkyl sulfonates or C–F bond activation of allylic gem-difluorides remain challenging. Herein, we report a nickel-catalyzed cross-electrophile coupling reaction between alkyl mesylates and all...

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Detalles Bibliográficos
Autores principales: Lin, Patricia C., Joshi, Chetan, McGinnis, Tristan M., Mallojjala, Sharath Chandra, Sanford, Amberly B., Hirschi, Jennifer S., Jarvo, Elizabeth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088041/
https://www.ncbi.nlm.nih.gov/pubmed/37066042
http://dx.doi.org/10.1021/acscatal.3c00257