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Population model‐based analysis of the memory B‐cell response following belimumab therapy in the treatment of systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by B‐cell hyperactivity and breach of tolerance. Autoreactive memory B cells, which have a decreased activation threshold and the ability to survive in absence of antigen, are believed to contribute to chronicity in autoimmune...

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Detalles Bibliográficos
Autores principales: Dimelow, Richard, Gillespie, William R., van Maurik, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088083/
https://www.ncbi.nlm.nih.gov/pubmed/36852495
http://dx.doi.org/10.1002/psp4.12919