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Baicalein alleviates TNF-α-induced apoptosis of human nucleus pulposus cells through PI3K/AKT signaling pathway

BACKGROUND: Nucleus pulposus (NP) cell apoptosis contributed to disc degeneration. Baicalein, a natural steroid saponin, has been demonstrated to have anti-inflammatory, antiapoptotic, and antioxidative effects in various diseases. However, little is known about the roles of baicalein in interverteb...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Liu, Dao-kuo, Wang, Zhi-wei, Zhao, Chong, Miao, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088118/
https://www.ncbi.nlm.nih.gov/pubmed/37041597
http://dx.doi.org/10.1186/s13018-023-03759-9