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Adipose-derived stem cells promote the repair of chemotherapy-induced premature ovarian failure by inhibiting granulosa cells apoptosis and senescence

BACKGROUND: Chemotherapeutic drugs, particularly alkylating cytotoxics such as cyclophosphamide (CTX), play an important role to induce premature ovarian failure (POF). Hormone replacement therapy (HRT) is a widely used treatment to improve hormone secretion. However, the long-term HRT increases the...

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Detalles Bibliográficos
Autores principales: Ai, Guihai, Meng, Meng, Guo, Jing, Li, Caixia, Zhu, Jihui, Liu, Li, Liu, Biting, Yang, Wenhan, Shao, Xiaowen, Cheng, Zhongping, Wang, Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088140/
https://www.ncbi.nlm.nih.gov/pubmed/37038203
http://dx.doi.org/10.1186/s13287-023-03297-5