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Whole-genome sequencing identifies novel predictors for hematopoietic cell transplant outcomes for patients with myelodysplastic syndrome: a CIBMTR study

Recurrent mutations in TP53, RAS pathway and JAK2 genes were shown to be highly prognostic of allogeneic hematopoietic cell transplant (alloHCT) outcomes in myelodysplastic syndromes (MDS). However, a significant proportion of MDS patients has no such mutations. Whole-genome sequencing (WGS) empower...

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Detalles Bibliográficos
Autores principales: Zhang, Tao, Auer, Paul, Dong, Jing, Cutler, Corey, Dezern, Amy E., Gadalla, Shahinaz M., Deeg, H. Joachim, Nazha, Aziz, Carlson, Karen-Sue, Spellman, Stephen, Bolon, Yung-Tsi, Saber, Wael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088148/
https://www.ncbi.nlm.nih.gov/pubmed/37041565
http://dx.doi.org/10.1186/s13045-023-01431-7