iPSC-derived cells lack immune tolerance to autologous NK-cells due to imbalance in ligands for activating and inhibitory NK-cell receptors

BACKGROUND: Dozens of transplants generated from pluripotent stem cells are currently in clinical trials. The creation of patient-specific iPSCs makes personalized therapy possible due to their main advantage of immunotolerance. However, some reports have claimed recently that aberrant gene expressi...

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Detalles Bibliográficos
Autores principales: Bogomiakova, Margarita E., Sekretova, Elizaveta K., Anufrieva, Ksenia S., Khabarova, Polina O., Kazakova, Anastasia N., Bobrovsky, Pavel A., Grigoryeva, Tatiana V., Eremeev, Artem V., Lebedeva, Olga S., Bogomazova, Alexandra N., Lagarkova, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088155/
https://www.ncbi.nlm.nih.gov/pubmed/37038186
http://dx.doi.org/10.1186/s13287-023-03308-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088155/
https://www.ncbi.nlm.nih.gov/pubmed/37038186
http://dx.doi.org/10.1186/s13287-023-03308-5

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