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Distinct CSF biomarker-associated DNA methylation in Alzheimer’s disease and cognitively normal subjects

BACKGROUND: Growing evidence has demonstrated that DNA methylation (DNAm) plays an important role in Alzheimer’s disease (AD) and that DNAm differences can be detected in the blood of AD subjects. Most studies have correlated blood DNAm with the clinical diagnosis of AD in living individuals. Howeve...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Young, Juan I., Gomez, Lissette, Schmidt, Michael A., Lukacsovich, David, Varma, Achintya, Chen, X. Steven, Martin, Eden R., Wang, Lily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088180/
https://www.ncbi.nlm.nih.gov/pubmed/37038196
http://dx.doi.org/10.1186/s13195-023-01216-7