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RA-RAR signaling promotes mouse vaginal opening through increasing β-catenin expression and vaginal epithelial cell apoptosis
BACKGROUND: Retinoic acid (RA) plays important role in the maintenance and differentiation of the Müllerian ducts during the embryonic stage via RA receptors (RARs). However, the function and mechanism of RA-RAR signaling in the vaginal opening are unknown. METHOD: We used the Rarα knockout mouse mo...
Autores principales: | Zheng, Nana, Zhang, Wenbo, Zhang, Xiaodan, Li, Biao, Wu, Zhanying, Weng, Yashuang, Wang, Weiyong, Miao, Jingjing, Yang, Jing, Zhang, Meijia, Xia, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088237/ https://www.ncbi.nlm.nih.gov/pubmed/37041518 http://dx.doi.org/10.1186/s12958-023-01084-8 |
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