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PhyloMed: a phylogeny-based test of mediation effect in microbiome
Microbiome data from sequencing experiments contain the relative abundance of a large number of microbial taxa with their evolutionary relationships represented by a phylogenetic tree. The compositional and high-dimensional nature of the microbiome mediator challenges the validity of standard mediat...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088256/ https://www.ncbi.nlm.nih.gov/pubmed/37041566 http://dx.doi.org/10.1186/s13059-023-02902-3 |