SDF-1α promotes subchondral bone sclerosis and aggravates osteoarthritis by regulating the proliferation and osteogenic differentiation of bone marrow mesenchymal stem cells

BACKGROUND: Subchondral bone sclerosis is a major feature of osteoarthritis (OA), and bone marrow mesenchymal stem cells (BMSCs) are presumed to play an important role in subchondral bone sclerosis. Accumulating evidence has shown that stromal cell-derived factor-1α (SDF-1α) plays a key role in bone...

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Detalles Bibliográficos
Autores principales: Meng, Zhiqiang, Xin, Lujun, Fan, Bosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088262/
https://www.ncbi.nlm.nih.gov/pubmed/37038152
http://dx.doi.org/10.1186/s12891-023-06366-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088262/
https://www.ncbi.nlm.nih.gov/pubmed/37038152
http://dx.doi.org/10.1186/s12891-023-06366-1

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