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Crystal structures of three homologues with increasing ring size: 2-meth­oxy-4-(thio­phen-2-yl)-5,6,7,8-tetra­hydro­quinoline-3-carbo­nitrile, 2-meth­oxy-4-(thio­phen-2-yl)-6,7,8,9-tetra­hydro-5H-cyclo­hepta­[b]pyridine-3-carbo­nitrile and 2-meth­oxy-4-(thio­phen-2-yl)-5,6,7,8,9,10-hexa­hydrocyclo­octa[b]pyridine-3-carbo­nitrile

The title compounds, C(15)H(14)N(2)OS (1a), C(16)H(16)N(2)OS (1b), and C(17)H(18)N(2)OS (1c), form a homologous series in which the size of the saturated ring increases from six- to eight-membered (with four, five and six methyl­ene groups respectively). For 1b and 1c, the central (CH(2))( n ) moiet...

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Detalles Bibliográficos
Autores principales: Hebishy, Ali M. S., Elgemeie, Galal H., Gouda, Lobna M., Jones, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088300/
https://www.ncbi.nlm.nih.gov/pubmed/37057025
http://dx.doi.org/10.1107/S2056989023001883