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High-throughput screening of spike variants uncovers the key residues that alter the affinity and antigenicity of SARS-CoV-2

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has elicited a worldwide pandemic since late 2019. There has been ~675 million confirmed coronavirus disease 2019 (COVID-19) cases, leading to more than 6.8 million deaths as of March 1, 2023. Five SARS-CoV-2 variants of concern...

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Detalles Bibliográficos
Autores principales: Luo, Yufeng, Liu, Shuo, Xue, Jiguo, Yang, Ye, Zhao, Junxuan, Sun, Ying, Wang, Bolun, Yin, Shenyi, Li, Juan, Xia, Yuchao, Ge, Feixiang, Dong, Jiqiao, Guo, Lvze, Ye, Buqing, Huang, Weijin, Wang, Youchun, Xi, Jianzhong Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088716/
https://www.ncbi.nlm.nih.gov/pubmed/37041132
http://dx.doi.org/10.1038/s41421-023-00534-2