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Inhibition of Aβ aggregation by naphtho-γ-pyrone derivatives from a marine-derived fungus, Aspergillus sp. MPUC239

Alzheimer’s disease (AD) is an important human disease that mainly causes cognitive impairments. Growing evidence has shown that amyloid-β (Aβ) peptide plays a key role in AD pathogenesis in what is known as the Aβ cascade hypothesis. This hypothesis suggests the importance of suppressing Aβ aggrega...

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Detalles Bibliográficos
Autores principales: Fujihara, Koji, Hashimoto, Takumi, Sasaki, Hiroaki, Koyama, Kiyotaka, Kinoshita, Kaoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088752/
https://www.ncbi.nlm.nih.gov/pubmed/37038034
http://dx.doi.org/10.1007/s11418-023-01696-9