Unveiling the Mechanistic Singularities of Caspases: A Computational Analysis of the Reaction Mechanism in Human Caspase-1

[Image: see text] Caspases are cysteine proteases in charge of breaking a peptide bond next to an aspartate residue. Caspases constitute an important family of enzymes involved in cell death and inflammatory processes. A plethora of diseases, including neurological and metabolic diseases and cancer,...

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Detalles Bibliográficos
Autores principales: Ramos-Guzmán, Carlos A., Ruiz-Pernía, J. Javier, Zinovjev, Kirill, Tuñón, Iñaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088814/
https://www.ncbi.nlm.nih.gov/pubmed/37066044
http://dx.doi.org/10.1021/acscatal.3c00037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088814/
https://www.ncbi.nlm.nih.gov/pubmed/37066044
http://dx.doi.org/10.1021/acscatal.3c00037

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